Guy, R. Kiplin: search on Z-Library

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1

Chemie und Biologie von Taxol

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Wei-Min Dai, Rodney Kiplin Guy

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 4.65 MB

german, 1994

2

A Selective Irreversible Inhibitor Targeting a PDZ Protein Interaction Domain

Fujii, Naoaki, Haresco, Jose J., Novak, Kathleen A. P., Stokoe, David, Kuntz, Irwin D., Guy, R. Kiplin

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 125 KB

english, 2003

3

Structure–activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells

Barnaby C.H. May, Juanita Witkop, John Sherrill, Marc O. Anderson, Peter B. Madrid, Julie A. Zorn, Stanley B. Prusiner, Fred E. Cohen, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

4

Chemistry and Biology of Taxol

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Wei-Min Dai, Mr. Rodney Kiplin Guy

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 2.82 MB

english, 1994

5

Synthese von C-2-analogen Taxolen

Prof. Dr. Kyriacos Costa Nicolaou, E. A. Couladouros, P. G. Nantermet, J. Renaud, Rodney Kiplin Guy, Wolfgang Wrasidlo

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 365 KB

german, 1994

6

Organocatalytic, Diastereo- and Enantioselective Synthesis of Nonsymmetric cis -Stilbene Diamines: A Platform for the Preparation of Single-Enantiomer cis -Imidazolines for Protein–Protein Inhibition

Vara, Brandon A., Mayasundari, Anand, Tellis, John C., Danneman, Michael W., Arredondo, Vanessa, Davis, Tyler A., Min, Jaeki, Finch, Kristin, Guy, R. Kiplin, Johnston, Jeffrey N.

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 2.67 MB

english, 2014

7

Structure-Guided Development of Selective TbcatB Inhibitors

Mallari, Jeremy P., Shelat, Anang A., Kosinski, Aaron, Caffrey, Conor R., Connelly, Michele, Zhu, Fangyi, McKerrow, James H., Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.39 MB

english, 2009

8

Parallel Synthesis and Antimalarial Screening of a 4-Aminoquinoline Library

Madrid, Peter B., Wilson, Nathan T., DeRisi, Joseph L., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2004

Language:

english

File:

PDF, 86 KB

english, 2004

9

Partial Acetylation of Lysine Residues Improves Intraprotein Cross-Linking

Guo, Xin, Bandyopadhyay, Pradipta, Schilling, Birgit, Young, Malin M., Fujii, Naoaki, Aynechi, Tiba, Guy, R. Kiplin, Kuntz, Irwin D., Gibson, Bradford W.

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 330 KB

english, 2008

10

Monitoring ligand-induced protein ordering in drug discovery

Grace, Christy R., Ban, David, Min, Jaeki, Mayasundari, Anand, Min, Lie, Finch, Kristin E., Griffiths, Lyra, Bharatham, Nagakumar, Bashford, Donald, Kiplin Guy, R., Dyer, Michael A., Kriwacki, Richard

Journal:

Journal of Molecular Biology

Year:

2016

Language:

english

File:

PDF, 834 KB

english, 2016

11

Ein wasserlösliches Prodrug von Taxol mit der Fähigkeit zur Selbstorganisation

Kyriacos Costa Nicolaou, Rodney Kiplin Guy, Prof. Dr. Emmanuel Nicolaou Pitsinos, Wolfgang Wrasidlo

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 822 KB

german, 1994

12

Synthesis and characterization of BODIPY-labeled colchicine

Leggy A. Arnold, Patricia Ranaivo, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

13

Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum: Role of β-haematin inhibition and drug concentration in vacuolar water- and lipid-phases

David C. Warhurst, John C. Craig, Ipemida S. Adagu, R. Kiplin Guy, Peter B. Madrid, Quinton L. Fivelman

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.11 MB

english, 2007

14

Global Phenotypic Screening for Antimalarials

W. Armand Guiguemde, Anang A. Shelat, Jose F. Garcia-Bustos, Thierry T. Diagana, Francisco-Javier Gamo, R. Kiplin Guy

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

15

Optimization of the electrophile of chloronitrobenzamide leads active against Trypanosoma brucei

Hwang, Jong Yeon, Smithson, David C., Holbrook, Gloria, Zhu, Fangyi, Connelly, Michele C., Kaiser, Marcel, Brun, Reto, Kiplin Guy, R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

16

Development of Potent Purine-Derived Nitrile Inhibitors of the Trypanosomal Protease TbcatB

Mallari, Jeremy P., Shelat, Anang A., Obrien, Terri, Caffrey, Conor R., Kosinski, Aaron, Connelly, Michele, Harbut, Michael, Greenbaum, Doron, McKerrow, James H., Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.79 MB

english, 2008

17

Podophyllotoxin analogues active versus Trypanosoma brucei

Md. Jashim Uddin, David C. Smithson, Kristin M. Brown, Brenda C. Crews, Michele Connelly, Fangyi Zhu, Lawrence J. Marnett, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 359 KB

english, 2010

18

Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis

Jong Yeon Hwang, David Smithson, Michele Connelly, Julie Maier, Fangyi Zhu, Kiplin R. Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

19

Parallel Synthesis of Diarylureas and Their Evaluation as Inhibitors of Insulin-Like Growth Factor Receptor

Anderson, Marc O., Yu, Hong, Penaranda, Cristina, Maddux, Betty A., Goldfine, Ira D., Youngren, Jack F., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

20

Proteomimetic Libraries: Design, Synthesis, and Evaluation of p53−MDM2 Interaction Inhibitors

Lu, Felice, Chi, Seung-Wook, Kim, Do-Hyoung, Han, Kyou-Hoon, Kuntz, Irwin D., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 333 KB

english, 2006

21

Inhibitors of the Interaction of a Thyroid Hormone Receptor and Coactivators: Preliminary Structure−Activity Relationships

Arnold, Leggy A., Kosinski, Aaron, Estébanez-Perpiñá, Eva, Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

22

Antimalarial activity of 10-alkyl/aryl esters and -aminoethylethers of artemisinin

Cloete, Theunis T., Krebs, Henk J., Clark, Julie A., Connelly, Michele C., Orcutt, Amy, Sigal, Martina S., Kiplin Guy, R., N’Da, David D.

Journal:

Bioorganic Chemistry

Year:

2013

Language:

english

File:

PDF, 310 KB

english, 2013

23

Discovery of Novel Antimalarial Compounds Enabled by QSAR-Based Virtual Screening

Zhang, Liying, Fourches, Denis, Sedykh, Alexander, Zhu, Hao, Golbraikh, Alexander, Ekins, Sean, Clark, Julie, Connelly, Michele C., Sigal, Martina, Hodges, Dena, Guiguemde, Armand, Guy, R. Kiplin, Tro

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 997 KB

english, 2013

24

Synthesis of C-2 Taxol Analogues

Prof. Dr. Kyriacos Costa Nicolaou, Elias A. Couladouros, Phillipe G. Nantermet, Joanne Renaud, Rodney Kiplin Guy, Wolfgang Wrasidlo

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 331 KB

english, 1994

25

An Inhibitor of the Interaction of Thyroid Hormone Receptor β and Glucocorticoid Interacting Protein 1

Geistlinger, Timothy R., Guy, R. Kiplin

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 53 KB

english, 2001

26

A Novel 2‘-( N -Methylpyridinium Acetate) Prodrug of Paclitaxel Induces Superior Antitumor Responses in Preclinical Cancer Models

Wrasidlo, Wolfgang, Gaedicke, Gerhard, Guy, Rodney Kiplin, Renaud, Johanne, Pitsinos, Emmanuel, Nicolaou, Kyriaco C., Reisfeld, Ralph A., Lode, Holger N.

Journal:

Bioconjugate Chemistry

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

27

A Facile One-Pot Synthesis of Symmetrical and Unsymmetrical Acetaldehyde Acetals from Primary Alcohols

Guy, Rodney Kiplin, DiPietro, Richard Anthony

Journal:

Synthetic Communications

Year:

1992

Language:

english

File:

PDF, 189 KB

english, 1992

28

Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition

Verras, Andreas, Waller, Chris L., Gedeck, Peter, Green, Darren V. S., Kogej, Thierry, Raichurkar, Anandkumar, Panda, Manoranjan, Shelat, Anang A., Clark, Julie, Guy, R. Kiplin, Papadatos, George, Bur

Journal:

Journal of Chemical Information and Modeling

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

29

A Water-Soluble Prodrug of Taxol with Self-Assembling Properties

Prof. Dr. Kyriacos Costa Nicolaou, Rodney Kiplin Guy, Emmanuel Nicolauo Pitsinos, Wolfgang Wrasidlo

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 747 KB

english, 1994

30

Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum

Marc O. Anderson, John Sherrill, Peter B. Madrid, Ally P. Liou, Jennifer L. Weisman, Joseph L. DeRisi, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 423 KB

english, 2006

31

Diverse amide analogs of sulindac for cancer treatment and prevention

Mathew, Bini, Hobrath, Judith V., Connelly, Michele C., Kiplin Guy, R., Reynolds, Robert C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 740 KB

english, 2017

32

A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships

Mathew, Bini, Snowden, Timothy S., Connelly, Michele C., Guy, R. Kiplin, Reynolds, Robert C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 339 KB

english, 2018

33

Phenotypic screens reveal posaconazole as rapidly cidal combination partner for treatment of Primary Amoebic Meningoencephalitis

Colon, Beatrice L, Rice, Christopher A, Guy, R Kiplin, Kyle, Dennis E

Journal:

The Journal of Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 967 KB

english, 2018

34

Correction: Cysteine modification reveals an allosteric inhibitory site on the CAL PDZ domain

Zhao, Yu, Cushing, Patrick R., Smithson, David C., Pellegrini, Maria, Pletnev, Alexandre A., Al-Ayyoubi, Sahar, Grassetti, Andrew V., Gerber, Scott A., Guy, R. Kiplin, Madden, Dean R.

Journal:

Bioscience Reports

Year:

2018

Language:

english

File:

PDF, 100 KB

english, 2018

35

Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain

Mark F Springsteel, Luis J.V Galietta, Tonghui Ma, Kolbot By, Gideon O Berger, Hong Yang, Christopher W Dicus, Wonken Choung, Chao Quan, Anang A Shelat, R.Kiplin Guy, A.S Verkman, Mark J Kurth, Michae

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 310 KB

english, 2003

36

Inhibition of a viral enzyme by a small-molecule dimer disruptor

Shahian, Tina, Lee, Gregory M, Lazic, Ana, Arnold, Leggy A, Velusamy, Priya, Roels, Christina M, Guy, R Kiplin, Craik, Charles S

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 891 KB

english, 2009

37

Correction to Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening

Lack, Nathan A., Axerio-Cilies, Peter, Tavassoli, Peyman, Han, Frank Q., Chan, Ka Hong, Feau, Clementine, LeBlanc, Eric, Guns, Emma Tomlinson, Guy, R. Kiplin, Rennie, Paul S., Cherkasov, Artem

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

38

Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439)

Kim, Ho Shin, Hammill, Jared T., Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 643 KB

english, 2017

39

Synthesis and Testing of a Focused Phenothiazine Library for Binding to HIV-1 TAR RNA

Moriz Mayer, P. Therese Lang, Sabina Gerber, Peter B. Madrid, Irene Gómez Pinto, R. Kiplin Guy, Thomas L. James

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 241 KB

english, 2006

40

Discovery of the First Irreversible Small Molecule Inhibitors of the Interaction between the Vitamin D Receptor and Coactivators

Nandhikonda, Premchendar, Lynt, Wen Z., McCallum, Megan M., Ara, Tahniyath, Baranowski, Athena M., Yuan, Nina Y., Pearson, Dana, Bikle, Daniel D., Guy, R. Kiplin, Arnold, Leggy A.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

41

Optimization of a Non-Radioactive High-Throughput Assay for Decarboxylase Enzymes

Smithson, David C., Shelat, Anang A., Baldwin, Jeffrey, Phillips, Margaret A., Guy, R. Kiplin

Journal:

Assay and Drug Development Technologies

Year:

2010

Language:

english

File:

PDF, 2.38 MB

english, 2010

42

Synthesis of Ring-Substituted 4-Aminoquinolines and Evaluation of Their Antimalarial Activities.

Peter B. Madrid, John Sherrill, Ally P. Liou, Jennifer L. Weisman, Joseph L. DeRisi, R. Kiplin Guy

Journal:

Year:

2005

Language:

english

File:

PDF, 23 KB

english, 2005

43

Reporting data from high-throughput screening of small-molecule libraries

Inglese, James, Shamu, Caroline E, Guy, R Kiplin

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.50 MB

english, 2007

44

ChemInform Abstract: Organocatalytic, Diastereo- and Enantioselective Synthesis of Nonsymmetric cis-Stilbene Diamines: A Platform for the Preparation of Single-Enantiomer cis-Imidazolines for Protein-Protein Inhibition.

Vara, Brandon A., Mayasundari, Anand, Tellis, John C., Danneman, Michael W., Arredondo, Vanessa, Davis, Tyler A., Min, Jaeki, Finch, Kristin, Guy, R. Kiplin, Johnston, Jeffrey N.

Journal:

Year:

2015

Language:

english

File:

PDF, 32 KB

english, 2015

45

Flexibility is important for inhibition of the MDM2/p53 protein–protein interaction by cyclic β-hairpins

Danelius, Emma, Pettersson, Mariell, Bred, Matilda, Min, Jaeki, Waddell, M. Brett, Guy, R. Kiplin, Grøtli, Morten, Erdelyi, Mate

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 908 KB

english, 2016

46

Evaluation of 1,1-cyclopropylidene as a thioether isostere in the 4-thio-thienopyrimidine (TTP) series of antimalarials

Barrows, Robert D., Hammill, Jared T., Tran, Michael C., Falade, Mofolusho O., Rice, Amy L., Davis, Christopher W., Emge, Thomas J., Rablen, Paul R., Kiplin Guy, R., Knapp, Spencer

Journal:

Bioorganic & Medicinal Chemistry

Year:

2020

File:

PDF, 1.13 MB

2020

47

Scaffold composition and biological relevance of screening libraries

Shelat, Anang A, Guy, R Kiplin

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 5.61 MB

english, 2007

48

Improvement of Pharmacological Properties of Irreversible Thyroid Receptor Coactivator Binding Inhibitors

Hwang, Jong Yeon, Arnold, Leggy A., Zhu, Fangyi, Kosinski, Aaron, Mangano, Thomas J., Setola, Vincent, Roth, Bryan L., Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

49

A Convenient Procedure for Parallel Ester Hydrolysis

Anderson, Marc O., Moser, Jamie, Sherrill, John, Guy, R. Kiplin

Journal:

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

50

Current and emerging therapy for improving outcomes in patients with intraocular retinoblastoma

Brennan, Rachel C, Pritchard, Eleanor M, Guy, R Kiplin, Dyer, Michael A, Wilson, Matthew W

Journal:

Expert Opinion on Orphan Drugs

Year:

2015

Language:

english

File:

PDF, 836 KB

english, 2015

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